Open-source software solutions for life science research

About Us

OpenBioSim develops and maintains biomolecular software that connect scientists developing computational methods with users in academia and industry.

We work with industrial partners to facilitate integration of open-source software solutions as components of technology platforms. We also provide ongoing software support and maintenance to open-source projects to ensure compatibility with our customer’s technology infrastructure.

Promoting and supporting the use of open-source biomolecular research software by academic and industrial communities.

Our Projects


BioSimSpace is the flagship product of OpenBioSim. It is a python framework to facilitate interoperability between popular molecular simulation software tools.



Sire is a molecular simulation framework that provides extensive functionality to manipulate representations of biomolecular systems.

It is used as a key component of BioSimSpace and provides a range of standalone CLI applications used for simulating protein-ligand interactions in pharmaceutical research. 

Latest news

Recent news and updates

Our Collaborators Include: